Searchable abstracts of presentations at key conferences in endocrinology

ea0070yi1 | Young Investigators | ECE2020

A mixed nutrient preload attenuates glucose-induced endothelial dysfunction in individuals with abnormal glucose tolerance

Trico Domenico , Nesti Lorenzo , Mengozzi Alessandro , Baldi Simona , Natali Andrea

Background: Postprandial hyperglycemia is an independent risk factor for cardiovascular disease and all-cause mortality. This excess cardiovascular risk may be partly explained by the impairment in endothelial function that typically follows an acute increase in plasma glucose levels. Recently, nutritional interventions focused on the sequence of macronutrient consumption within the meal have been proposed to normalize postprandial glycemia in subjects with abnormal glucose to...

ea0070aep256 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Fatty liver, irrespective of ethnicity, is associated with reduced insulin clearance and insulin resistance in obese youths

Trico Domenico , Galderisi Alfonso , Galuppo Brittany , Pierpont Bridget , Samuels Stephanie , Santoro Nicola , Caprio Sonia

Background: Non-Alcoholic Fatty Liver Disease (NAFLD) is the most common chronic liver disease in Western countries and identifies people at high risk to develop metabolic and cardiovascular disease. Fatty liver has been associated with reduced endogenous insulin clearance (EIC) and hepatic insulin resistance (HIRI), which are early features of type 2 diabetes. These relationships however might be differentially affected by the ethnic background, as populations of African ance...